Liggins Institute


Felicia Low

c-felicia-low.jpg

Research Fellow
Office of the Prime Minister’s Science Advisory Committee
BSc, MSc(Hons), PhD

Contact details

Phone: +64 9 923 4489
Email: f.low@auckland.ac.nz

Key research interests

  • Epigenetics
  • Developmental Origins of Health and Disease
  • Dissemination and translation of scientific research
Profile

Felicia Low is a biochemist who obtained her PhD from the University of Otago, New Zealand. Her research, undertaken at the Free Radical Research Group in Christchurch, focused on the unusual antioxidant properties of an erythrocyte enzyme and its ability to protect haemoglobin from oxidative denaturation. She then joined the National Research Centre for Growth and Development, a Centre of Research Excellence based at the Liggins Institute, where she handled communications work for the Centre and scientific writing for then-Director Professor Sir Peter Gluckman. Felicia is currently a Research Fellow with Sir Peter, the Prime Minister’s Chief Science Adviser.
Office of the Prime Minister’s Science Advisory Committee.

She is a member of the Liggins Institute’s Centre for Human Evolution, Adaptation and Disease.

Key publications
  1. Low FM, Tng E and Gluckman PD. ‘Epigenetic mechanisms’ In G Buonocore, R Bracci and M Weindling (eds.) Neonatology. Milan, Springer-Verlag Italia; p 26–30, 2012 http://www.springer.com/medicine/pediatrics/book/978-88-470-1404-6
     
  2. Low FM, Gluckman PD, Hanson MA. Developmental plasticity, epigenetics and human health, Evolutionary Biology, DOI 10.1007/s11692-011-9157-0, published online 10 Jan 2012.
    http://www.springerlink.com/content/57t35556351832h8/
     
  3. Low FM, Gluckman PD and Hanson MA. ‘Developmental plasticity and epigenetic mechanisms underpinning metabolic and cardiovascular diseases’, Epigenomics, 3, p 279–294, 2011
    http://www.futuremedicine.com/doi/abs/10.2217/epi.11.17.

  4. Buklijas T, Low FM, Beedle AS, Gluckman PD. Developing a curriculum for evolutionary medicine: case studies of scurvy and female reproductive tract cancers, Evolution: Education and Outreach, 4, p 595–602, 2011
    http://www.springerlink.com/content/72805314h2601u35/
     
  5. Gluckman PD, Low FM, Franko KL. Puberty and adolescence: transitions in the life course. Improving the Transition: Reducing Social and Psychological Morbidity During Adolescence. Auckland: Office of the Prime Minister's Science Advisory Committee, p 19–34, 2011
    http://www.pmcsa.org.nz/improving-the-transition/ 
     
  6. Gluckman PD, Low FM, Buklijas T, Hanson MA and Beedle AS. ‘How evolutionary principles improve the understanding of human health and disease’, Evolutionary Applications, 4, p 249-263, 2011.
     
  7. Gluckman PD, Hanson MA, Beedle AS, Buklijas T and Low FM. ‘Epigenetics of Human Disease’. In B Hallgrímsson and BK Hall (eds.) Epigenetics: Linking Genotype and Phenotype in Development and Evolution. Berkeley, University of California Press; p 398-423, 2011
     
  8. Gluckman PD, Hanson MA, Buklijas T, Low FM and Beedle AS. 'Epigenetic mechanisms that underpin metabolic and cardiovascular diseases', Nature Reviews Endocrinology, 5, p 401–408, 2009
     
  9. Low FM, Hampton MB and Winterbourn CC. 'Peroxiredoxin 2 and peroxide metabolism in the erythrocyte', Antioxidants & Redox Signaling, 10, p1621–1629, 2008
     
  10. Peskin AV, Low FM, Paton LN, Maghzal GJ, Hampton MB and Winterbourn CC. 'The high reactivity of peroxiredoxin 2 with H2O2 is not reflected in its reaction with other oxidants and thiol reagents', Journal of Biological Chemistry, 282, p11885–11892, 2007
     
  11. Low FM, Hampton MB, Peskin AV and Winterbourn CC. 'Peroxiredoxin 2 functions as a noncatalytic scavenger of low-level hydrogen peroxide in the erythrocyte', Blood, 109, p2611–2617, 2007
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