Dong-Xu Liu

Senior Research Fellow
BSc, MSc, PhD

Contact details

Phone: +64 9 923 9603
Email: dx.liu@auckland.ac.nz

Key research interests

• Breast cancer biology
• Growth hormone signaling
• Oncogenes
• Molecular therapeutics
   

1987: BSc, China Agricultural University, Beijing.
1992: MSc, Chinese Academy of Sciences: Chengdu Institute of Biology.
2000: Ph.D., National University of Singapore.
I have strong interests in the molecular biology of cancer especially breast cancer. I have identified several potential key genes that are involved in the ontogenesis of breast cancer; molecular therapeutics targeting novel oncogenes; I have two patents filed so far.

1. Pandey V, Qian PX, Kang J, Perry JK, Mitchell MD, Yin Z, Wu ZS, Liu DX, Zhu T, and Lobie PE. Artemin stimulates oncogenicity and invasion of endometrial carcinoma cells. In press (2010), Endocrinology.

2. Vidal LJP, Perry JK, Vouyovitch C, Brunet-Dunand SE, Mertani HC, Liu DX, Lobie PE. PAX5α enhances the epithelial behaviour of human mammary carcinoma cells. In press (2010), Molecular Cancer Research.

3. Tang JZ, Zuo ZH, Kong XJ, Steiner M, Yin Z, Perry JK, Zhu T, Liu DX, and Lobie PE. STAT5A and STAT5B differentially regulate human mammary carcinoma cell behaviour. In press (2010), Endocrinology.

4. Amiry N, Kong X, Muniraj N, Kannan N, Grandison PM, Lin J, Yang Y, Vouyovitch CM, Borges S, Perry JK, Mertani HC, Zhu T, Liu DX and Lobie PE. (2009) TFF1 enhances oncogenicity of mammary carcinoma cells. Endocrinology, 150, 10, 4473-83.

5. Kang J, Perry JK, Pandey V, Fielder GC, Mei B, Qian P, Zhu T, Liu DX and Lobie PE. (2009) Artemin is oncogenic for human mammary carcinoma cells. Oncogene, 28, 19, 2034-45.

6. Liu DX, Lobie PE. Transcriptional regulation of p53 by PitX1 (2007) Cell Death & Diff 14, 1893-1907.

7. Gorba, T, Bradoo, P, Liu, DX, Lobie, PE, Gluckman, PD and Sieg, F (2006) Neural regeneration peptides: A novel class of chemoattractive and neuronal survival promoting proteins. Exp Cell Res 312, 3060-74.

8. Mukhina, S, Liu, DX, Ge, K, Raccurt, M, Bendriss, S, Mertani, HC and Lobie PE (2006) Autocrine growth hormone prevents lactogenic differentiation of mouse mammary epithelial cells. Endocrinology 147: 1819-29.

“Cancer is a preventable disease that will eventually be curable through the advances in medicine offered by the molecular targeting of novel oncogenes.”